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doi: 10.3389/fmed.2016.00038 Received 03 July 2016 Accepted 09 August 2016 Published 23 August 2016 Volume 3 - 2016 Edited by Mohammed Morad, Clalit Health Services, Israel Reviewed by Luciana Hannibal, University Medical Center Freiburg, Germany

Diminished production of NADH in the Krebs cycle also results in lactic acid production through facilitation of anaerobic glycolysis

In this study, we aimed to identify the clinical factors and single-nucleotide polymorphisms (SNPs) associated with the toxicity and efficacy of pemetrexed chemotherapy