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Mutation and immune profiles in early-stage lung squamous cell carcinoma

Chronic hyperglycemia impairs neutrophil chemotaxis, oxidative burst, and complement activation, while vascular insufficiency and neuropathy compromise tissue perfusion and barrier integrity

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In sum, in proteo-stressed touch neurons, tagged intermediate filaments IFD-1 and IFD-2 concentrate into juxtanuclear foci that have subcellular localization features akin to those described for mammalian aggresomes