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[30] This guidance remains relevant, if not more so, during treatment with agents that affect the gastrointestinal tract

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Stage 10: Purposeful and Functionally Independent At this last phase, patients have regained control over their lives, can handle daily responsibilities, and make decisions without assistance

Several researchers have proposed intranasal delivery to reduce first-pass degradation and allow direct olfactory-pathway CNS access

250 Therefore, targeting dyslipidemia and its downstream effects may offer promising therapeutic avenues for DPN management (Fig