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Fosgonimeton is a phosphate prodrug of Dihexa developed by Athira Pharma (formerly M3 Biotechnology)

The concept of Virtual Physiological Human (VPH), first described in a white paper in 2005, envisions the development of patient-specific computer models that support clinical decision-making by forming virtual patient groups to test the safety and efficacy of new drugs and medical devices [204,205]

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Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder