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That the show as a disaster in every conceivable measure except for the predictable ratings was the final nail in most peoples willingness to grant SNL the benefit of the doubt, or pay any attention to Lornes tiresome comedy means hitting both sides equivocation

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Talking and talking while we blew smoke in one anothers faces

Considering the rate of MVP observed in our cEDS cohort and the knowledge that the mitral valve depends upon collagen for its tensile strength and that myxomatous MVP is characterized by disruption of the collagen layer with expansion of glycosaminoglycans within the middle layer of the valve [123], it is reasonable to consider MVP as a potential clue for cEDS, although the true clinical significance is so far unknown

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