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For individuals significantly above 250 pounds, extended protocols of 16-20 weeks rather than higher daily doses often produce better outcomes

Cloning and site-directed mutagenesis All plasmids and primers for cloning and site-directed mutagenesis are listed as separate Supplementary Data

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Antioxidant interventions that restore glutathione activity (including selenium supplementation, which activates GPx) have demonstrated significant reductions in TPO antibodies and oxidative stress markers in clinical trials