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WADA Prohibition The World Anti-Doping Agency classification for these peptides: GLP3 likely classified under prohibited substances as a GLP-1 receptor agonist Cagrilintide status as amylin analog may fall under peptide hormone prohibitions Combined formulation would be prohibited under multiple substance categories No Therapeutic Use Exemptions (TUEs) available for either component Detection methods under development for anti-doping testing WADAs position reflects that these remain investigational agents without regulatory approval from health authorities worldwide

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A combination of folate and cobalamin has also been successfully used in rodents, in which it reduced cardiac damage in a model of isoproterenol-induced myocardial infarction in rats with HHCY [231], proving the ability of such supplementation to lower homocysteine levels with subsequent protection of the heart