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Gynecol Obstet Investig 53(Suppl

For example, ROS is produced in several ways in the mitochondria, and succinate oxidation is one of the ways to generate ROS during NAD-linked substrates, such as coupled respiration with succinate in complex I via reverse electron transfer from complex II to I

Finally, dietary Met supplementation in female rats (7.7 g/kg per kg of diet), 3 weeks prior to and during pregnancy, led to a significant reduction in H 2 S levels in the brains of the offspring [59], while treatment of mice with Hcy (0.03 mol/g BW, twice a day for 30 days, subcutaneously) decreased H 2 S production in the brain [60]

Future studies should explore these mechanisms through ongoing research and technological advancements, thereby providing more scientifically grounded guidance for both basic research and clinical applications

Med Hypotheses 61:5255 Vanderheiden A, Klein RS (2022) Neuroinflammation and Covid-19