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For example, the inhibition of histone deacetylases or demethylases interferes with the chromatin modifications that maintain DTP cells in a drug-tolerant state, such as the retention of closed or repressed chromatin at pro-apoptotic loci, thereby restoring susceptibility to drug-induced apoptosis (55)

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It's all part of the larger goal of bringing better PD therapies to patients as quickly as possible

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Une tude mene en Italie a ainsi montr que chez les patients de moins de 80 ans, les cas mortels taient beaucoup plus frquents chez les hommes, qui ont des niveaux plus faibles de Glutathion rduit dans le sang (1)