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10.1080/13880209.2021.1961820 219 XuW.DuX.LiJ.ZhangZ.MaX.LuoD.et al (2022a)

Researchers believe that methotrexate slows the progression of RA and relieves symptoms by causing cells to release a molecule called adenosine, which blocks other chemicals that promote inflammation, explains Edwin Chan, MD, a rheumatologist and researcher at the New York University School of Medicine