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Upregulated GH receptor mRNA and protein in tendon fibroblasts Effect was dose-dependent and observed within 24 hours Provides a mechanistic link between BPC 157 and tissue growth/repair BPC 157 and blood vessels2019Vascular Review of BPC 157s vascular effects: promotes angiogenesis, protects endothelium, and counteracts vascular disruption in multiple injury models including thrombosis and ischemia-reperfusion

Zinc transporter 10 (ZnT10)-dependent extrusion of cellular Mn 2+ is driven by an active Ca 2+ -coupled exchange

Key Benefits* Supports healthy muscle, tendon, and ligament function Promotes normal tissue recovery and regeneration Encourages skin health and post-activity repair Helps maintain gut lining integrity and digestive function Supports vascular health and nitric oxide pathways Promotes cellular renewal for healthy aging Helps the body respond to oxidative and environmental stressors *These statements have not been evaluated by the Food and Drug Administration

doi: 10.1136/jitc-2020-000695 36 ZalfaCPaustS

H&Y scale classifies severity of PD associated motor symptoms (158)