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PMCID: PMC4890704

Mechanism understanding helps troubleshooting non-responders, switching to peptides targeting different pathways potentially more relevant for specific individual pathophysiology

Mov Disord 34:138141 Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C (2007) Peroxisome Proliferator-Activated Receptor- Contributes to the Anti-Inflammatory Activity of Glucocorticoids

Although the AMPK and activating transcription factor 4 (ATF4) pathways have previously been implicated in GLUT1 regulation, our findings indicate that metformin-induced GLUT1 upregulation occurs independently of both

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