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Differentially expressed (DE) genes were recognized using the cut-off criteria, fold change (FC) - 2 or 2, ANOVA, p 1.3) with significant z-score 2 have been enlisted in Table 4

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ROS damages Leydig cells, disrupts the HPG axis, and interferes with NO bioavailability, a critical molecule for erectile function [129]

Of note, these regulatory pathways may be interconnected and influence the dynamic autophagic process at different steps