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However, hordenine is naturally present in cactus species, barley and other plants

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When the balance tips in favour of the toxic molecules , however, this referred to as oxidative stress

It acts as a copper-binding tripeptide naturally present in human plasma that upregulates collagen and glycosaminoglycan synthesis, stimulates angiogenesis, and activates antioxidant gene expression (SOD, catalase)

During oxidative metabolism, O 2 is employed as the terminal electron acceptor for mitochondrial electron transport chain (ETC)