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Furthermore, in clinical settings, functional medicine doctors often utilize Intravenous (IV) Vitamin C for severe ME/CFS or Long COVID crashes, as IV administration bypasses the gut entirely, achieving pharmacological plasma concentrations up to 70 times higher than oral dosing to rapidly quench systemic oxidative stress

Croat Med J

In both the entire SNpc and its dorsolateral subregion containing nigrosome 1, QSM values were markedly higher in PD patients, with iron accumulation being more pronounced in the dorsolateral SNpc (216)

doi: 10.1152/ajpgi.2000.279.2.G417

Continue daily during loading (7 to 21 days depending on skin type), then switch to 0.5 mg once or twice weekly for maintenance