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PUFAs evoke an inflammatory response of Gpx4 -deficient IECs To analyze the role of GPX4 in IECs, we first generated Gpx4 / small intestinal epithelial MODE-K cells by CRISPR Cas9 editing of exon 1 26 , which induced IEC death and thus prevented further studies (Supplementary Fig

Observed intra-individual variations in GSH levels are typically much smaller in animals utilized in laboratory research (CV =13 % in mosquitos and 8 % in mice) [14, 15, 17]

Therefore, the decay kinetics of GSNO based on absorption spectroscopy should agree with the NO generation kinetics

Rivas AS, lvarez YE, Cordellat AB, Tarruella MM, Mata KM, de la Cmara MM, et al

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