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Thyroid hormone replacement therapy restores ovulation and improves outcomes, and even subclinical cases benefit from treatment when TSH is optimised to preconception targets

To elicit neuronal firing, MSNs were held at 70 mV with direct current injections in the current clamp configuration, using bridge compensation, and depolarization was provided by 5-s long current ramps of increasing magnitude (maximal current ranging from 50 to 300 pA)

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In case of overdose, call a Poison Control Centre or get medical help right away