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Quercetin-induced pyroptosis in colon cancer through NEK7-mediated NLRP3 inflammasome-GSDMD signaling pathway activation

presented a heterozygous CHAC1 deletion mouse model that was protected from kidney disease progression across three different disease models, without any known phenotypic changes under control conditions ( Despite its injury-promoting effects in some organs, CHAC1 contributes to tissue repair in certain contexts

Paneco, 135), while the other part was seeded on plastic plates (Corning) and cultured for no longer than 8 passages in RPMI growth medium (Paneco, 330) supplemented with 10% FBS, 2 mM glutamine (Gibco, #35050061), 1% penicillin/streptomycin (Paneco, A065), and 1% non-essential amino acids (Paneco, 115/100)

This study is performed in accordance with relevant guidelines and regulations

While our bodies are amazing, our natural glutathione levels can decline due to a variety of factors: aging, stress, poor diet, environmental toxins, and even intense physical activity