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When this DNA repair pathway is not functional, cells are more sensitive to compounds that can damage the DNA such as DNA interstrand-crosslinking (ICL) agents and simple aldehydes 11

The same molecular dynamic was established for the antioxidant system: young ocean quahogs exhibit high antioxidant capacity compared to other bivalves, but then, at age of 30, the mitochondrial citrate synthase as well as the catalase and glutathione stabilize at lower post-maturation levels and show no tendency for further decline with age ( A

[DOI] [PubMed] [Google Scholar] 201.Honarmand M., Namazi F., Mohammadi A., Nazifi S

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Through a division of labor, these domains cooperatively construct a conformationally mature :2 hemicomplex that is competent for subsequent steps in AP2 assembly