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A copper peptide serum bypasses the outer barrier and gets the peptide where it needs to be

Regulated proteasome degradation finetunes the protein levels of HIF1a depending on the tissue oxygen availability [9]

N Engl J Med 368:651662

In this review, we not only gathered the most recent discoveries on MTHFR polymorphism and related DNA methylation in various psychiatric disorders, but also highlighted the potential relationships between MTHFR activity and implication of folate-related function in specific mental diseases