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Impaired renal clearance may also elevate prolactin levels, further hindering gonadotropin-releasing hormone (GnRH) function and exacerbating hypogonadism [139]

This suggests that hyperglycemia suppressed catalase expression [92,93,94]

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10.1096/fj.202002151r [DOI] [PMC free article] [PubMed] [Google Scholar] Visioli F, Ingram A, Beckman JS, Magnusson KR, Hagen TM (2022) Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help

Pharmacokinetics in mice BALB/c nude mice (4-week-old) were purchased from the Chinese Academy of Science, and all procedures for the in vivo nude mice study were approved by the Animal Care Committee of Chongqing Medical University