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1.1 Emerging role of dietary interventions Recent research suggests that certain dietary patterns can influence essential pathophysiological characteristics of AD, such as neuroinflammation, oxidative stress, and amyloid-beta deposition (Stefaniak et al., 2022)

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Artesunate treatment of COPD rats reduces IL-6, IL-8, TNF-, and ICAM-1 expression, reverses smoking-induced increase in ROS levels and reduction in GSH levels, and attenuates inflammatory infiltration and oxidative stress (Pan et al., 2021)

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Nasal-brain pathway The nasal brain pathway is a promising way to promote drug delivery into the brain