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Reducing brain-generated acetaldehyde by silencing catalase or increasing ALDH2 activity in the VTA decreases alcohol-induced-reinforcing effects and reduces voluntary ethanol intake (141)

Some employers have recently stopped coverage due to increasing costs, with healthcare systems reporting monthly expenses rising from $1.5 million to $5 million for these medications

Treatment The only effective treatment is oral T4 usually referred to as levothyroxine and occasionally thyroxine

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At Phase 3 (1.0 mg/week), you use 30 units per injection