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Although several preclinical anti-cancer outcomes have been achieved, such as with ferroptosis inducers, translating oxidative cell death mechanisms into effective clinical therapies requires rigorous testing, including assessments of bioavailability, toxicity, and off-target effects

Tofacitinib for the treatment of ulcerative colitis: an integrated summary of up to 7.8 years of safety data from the global clinical programme

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Zhou Y, Liang Z, Xia Y, Li S, Liang J, Hu Z