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In psoriatic skin, NF-kB is constitutively activated, meaning it stays turned on even without an ongoing trigger

Effectiveness of hydrolyzed collagen peptide injection for the treatment of collateral ligament pain: A randomized controlled trial

Thompson JA, Schneider BJ, Brahmer J, et al

It functions as an osmolyte that helps regulate intracellular water content and electrolyte balance, thereby maintaining proper cell hydration and volume