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This highlights the ability of Affimer proteins to select novel conformers of target proteins to reveal druggable regions on protein surfaces concurrent with pharmacophore identification

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Cryosectioning PFA-fixed organoids were transferred to a cryomold, embedded in OCT compound (Thermo Fisher Scientific) and cooled to 80 C in a bath of isopropanol on dry ice

Most recently, ChIP-Seq was used to identify AREs on the Igf-1 locus in skeletal muscle mesenchymal progenitors (ie., fibro-adipogenic progenitor cells, FAPs)

Kuroda J, Kimura S, Strasser A, Andreeff M , Ashihara E, Tabe Y, Taniwaki M, Maekawa T