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Puccio et al., 2001

Furthermore, methotrexate (MTX), the immunosuppressant commonly used for the treatment of RA, has been demonstrated that could reduce inflammation and subsequent tissue damage by inhibiting MAA-adducts formation and scavenging superoxide in RA [108]

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Aged T cells resist ferroptosis by limiting labile iron pool via downregulation of IRP2 One mechanism by which cells resist ferroptosis is by restriction of labile iron pool 21

Farina et al., 2005)