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We show that ALA treatment is effective at increasing antioxidant levels, lowering oxidative stress-related changes in protein and nucleic acid and protecting retinal ganglion cells in the DBA/2J glaucomatous retina

Nicotinamide N-methyltransferase (NNMT) inhibition increases energy expenditure and decreases fat storage, two important aspects of treating insulin resistance, a defining feature of type 2 diabetes

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