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Moreover, PEGylated PLGA (PEG-PLGA) thermosensitive hydrogels nsTPPgels with non-shrinking properties loaded with bispecific anti-prostate-specific antigen (PSMA) Fab/anti-CD3 scFv T cell engagers (BiPTE), can promote CTLs migration to tumor sites and initiate T cells immunotherapy through the PSMA-targeting arm on BiPTE thereby enhancing the therapeutic effect against solid tumors (153)