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Despite these improvements, significant diagnostic delays persisted, particularly those patients with predominantly nonmotor or atypical symptoms [50]

These organ systems exemplify how immune cell mitochondrial dysfunction can influence surgical recovery and how interventions targeting these pathways have fared clinically ( Figure 7 )

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In addition, recent studies have indicated that inhibiting or alleviating inflammation by reducing macrophages and inhibiting inflammatory factors can reduce the cyst burden and improve kidney function