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Nat Rev Drug Discovery (2003) 2(9):72735

Early clinical studies Recent advances in the study of EVs, particularly MSC-EVs, have propelled these EV-based therapies into the forefront of AD research, with some formulations progressing into preclinical and early-phase clinical trials

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Summary: Cagrilintide (a cagri peptide) combined with retatrutide is a hypothetical investigational pairing with no published clinical trial data or UK regulatory approval, though each agent individually shows significant promise for obesity treatment