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Apart from collagen degradation owing to excessive MMP expression, ROS also triggers a decrease in collagen production by inhibiting the TGF- signal pathway (75)

Since stress-responsive cis -acting elements existed in the promoters of the RcGPXs , qRT-PCR was performed to investigate the expression change of RcGPXs under cold, drought, and salt stresses (Figure 4)

4 Discussion Selenium, iron, and vitamin E intake were increased in supplemented animals throughout the experimental period and changes in the concentrations of blood metabolites of animals were observed, indicating their supportive role against pathogens