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Meanwhile, the hydrogel matrix, exhibiting ROS-scavenging capabilities, has been engineered to be an intelligent drug reservoir for wound-responsive release of D-CuP at the wound site while simultaneously attenuating inflammatory responses

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Although some research suggests that L-carnitine might improve blood sugar control in people with diabetes, most research shows that L-carnitine does not have this effect

When applied for a total period of 9 months, it was shown to significantly reduce skin thickening and induration with minimal and well-tolerated side effects, except for one pediatric patient that required temporary discontinuation due to skin ulceration (132, 133)