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J Pharmacol Exp Ther 267:211217 Xu W, Wang X, Tocker AM et al (2017) Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists

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The concentration of NO produced under such conditions can be even 1000 times higher than the concentration of NO produced by constitutive NOS (neuronal NOS, nNOS, or endothelial NOS, eNOS)