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Dyclonine has been used as an oral anesthetic administered in throat lozenges and is known to inhibit Nav1.8, a voltage-dependent Na channel primarily expressed on small, unmyelinated peripheral sensory neurons, most of which are nociceptors 94

Similarly, they have also modulated parameters linked with adipose tissue reduction, wound healing, and neuroprotection in organisms during clinical studies

Common side effects include injection site reactions, mood swings, and mild ovarian enlargement

This suggests that GHK-Cu treatment, particularly the lower dose, contributed to better knee stability in the early healing phase

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