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Clinical trials suggest retatrutide produces greater weight loss than these existing medications

808 On the other hand, mass spectrometry has the advantage of detecting very low concentrations of metabolites but often lacks reproducibility due to the influence of various ions or proteins in the samples and cannot be directly used for in vivo detection

Further, deep cell layers, such as the mesophyll or vascular tissue, are accessible and the high resolution (~ 0.2 nm) of a TEM allows the visualization of even local, subcompartmental changes

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doi: 10.3389/fphar.2026.1694895 Received 29 August 2025 Revised 30 November 2025 Accepted 12 January 2026 Published 13 February 2026 Volume 17 - 2026 Edited by Ji Yichun, University of California, San Diego, United States Reviewed by Janina P