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Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy

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doi: 10.1001/archpsyc.1965.01730060001001

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PATHOPHYSIOLOGY The process by which INH toxicity occurs is complex but includes two main mechanisms, which have the overall effect of depleting gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the central nervous system (CNS)