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Statements Author contributions RB and MM conceived and co-wrote the main manuscript

Nanoparticles were designed with a 2,2-(propane-2,2-diylbis(sulfanediyl)) bis(ethan-1-ol) linker that could be oxidized by ROS, decompose into oligomeric units, and release the ruthenium catalyst

While research on long-term continuous use remains limited, the consensus among experienced users and researchers favors cycling to maintain optimal response to subsequent protocols

Not surprisingly, the trend of recommending and administering intravenous glutathione has increased within months of it becoming available, despite the potential adverse effects and lack of evidence