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Carozzi VA, Marmiroli P, Cavaletti G

The global burden of multiple chronic conditions: a narrative review

The most common adverse reactions that have been reported with topical azelaic acid formulations are burning, itching, stinging, dryness, and erythema which are temporary and mild (Kirsch et al., 2019

An important role of Nrf2-ARE pathway in the cellular defense mechanism

ILC2s are capable of both initiating and propagating many of the pathological features of allergic airways disease, potentially playing a critical role in acute disease exacerbations ( -/- mice, cultured for 24h in the presence or absence of melatonin, and then adoptively transferred the ILC2s into Rag2 -/- GC -/- mice utilizing established protocol as described by our group previously ( Figure 4A )