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About this article Cite this article Sugiyono, Ulhaq, Z.S

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Additionally, SIRT1 modulates the activity of forkhead box O (FOXO) transcription factors, which activate the expression of enzymes involved in ROS detoxification, including SOD2 (superoxide dismutase 2) and catalase, thereby attenuating oxidative stress-induced apoptosis [51]

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Design, synthesis and biological evaluation of brain targeting l-ascorbic acid prodrugs of ibuprofen with lock-in function