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In addition, a consolidated overview of the biological effects of PYC, categorized by study type and quality of evidence, is provided in Table 2

Nature Aging, 4 (12), 1772

This metabolic activity may involve the (reverse) conversion of IDH1 to isocitrate in the cytoplasm

As discussed elsewhere [10], the pool of glutamate involved in synaptic transmission is much smaller than that associated to energy metabolism (Fig

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