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Feb 2009;27(1):39-50, viii

Cell Res 30(2):146162

Anastasilakis AD, Polyzos SA, Saridakis ZG, Kynigopoulos G, Skouvaklidou EC, Molyvas D, et al

Pharmacological inhibition has demonstrated therapeutic potential

However, some users report cardiovascular effects including rapid heartbeat, chest pain, or dizziness, particularly with excessive application or use on compromised skin barriers