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[CrossRef] [PubMed] [Google Scholar] Selenomethionine alleviates decabromodiphenyl ether-induced oxidative stress and ferroptosis via the NRF2/GPX4 pathway in the chicken brain

Further findings (102) reveal that iron overload leads to the increase of MMP and the accumulation of lipid peroxide by affecting GSH and fatty acid cycle, which further promotes the activation of osteoclasts and apoptosis of osteoblasts, leading to increased bone resorption and decreased bone formation

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It is also possible that damage via the carbonyl stress pathway may only occur at a local level limited to renal tissue