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The ability of IL-1 to induce chondrocyte catabolism [121] has been well known for a long time, but it is only recently that IL-1 has been shown to disrupt chondrocyte iron homeostasis [117] and trigger chondrocyte ferroptosis [22, 122]

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doi: 10.1097/01.mpa.0000153326.69816.7d 6 ChenLLiuTZhouJWangYWangXDiWet al

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It also inhibits the survival of cancer cells through a proapoptotic mechanism

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PubMed Google Scholar 98.Puddu P, Puddu GM, Galletti L, Cravero E, Muscari A, Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis[J]

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