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Description

The documented pattern is simply a steady daily presence of the inhibitor, held long enough for the downstream metabolic change to accumulate

doi: 10.3389/fphar.2024.1402138 96 LaferrreBHartABBowersCY

2021;54:797814.e796

In this study, the high molecular weight HA used in combination with AOD9604 may have further supported chondrocyte survival and matrix synthesis, contributing to the observed improvements in cartilage morphology and function