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Important considerations include: Avoiding use with serotonin-increasing medications such as SSRIs as there is risk of serotonin syndrome when combined with those drugs Avoiding use in individuals with G6PD deficiency Consulting a physician before considering its use He also highlights the importance of quality

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Gut symptoms often show first improvements within 2 to 4 weeks, while tendon and ligament changes usually begin around 3 to 4 weeks after a protocol that had stalled in physical therapy