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In contrast, only slight green fluorescence was observed in cells treated with Bi 2 S 3 + X-ray, indicating the contribution of 3BP for ROS generation and providing a solid basis for achieving RT enhancement under hypoxic conditions

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These stimuli first activate MEKK1-4, TAOs, transforming growth factor B activating kinase (TAK) and ASK, which mediate the p38 pathway and gradually activate MAPK kinases (MEK3/6) and p38 isoforms