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IGFBPs thus act both as carriers of IGF, prolonging its half-life, and as modulators of IGF availability and activity ( Figure 1E )

(2024) 10:e24042

[PubMed: 11433352] 799

Results: Of the 63 patients, the mean age was 49 years, 65% were male, 17% were cirrhotic, 67% were treated with ETV, and the median treatment duration was 3 years