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Maintenance therapy for patients with neurological involvement may also be more frequent, sometimes every two months rather than three, though this should be individualised based on clinical response

Homocysteine accumulates in the blood when there is inadequate folate and/or vitamin B 12 for effective functioning of the methionine synthase enzyme (see Function)

A deficiency in vitamin B12 can lead to anemia and neurological issues, which is why maintaining adequate levels is essential