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[Google Scholar] 70.Dolashki A, Voelter W, Gushterova A, et al

The transcription factor NFE2L2 (Nrf2) positively regulates SLC7A11 expression, whereas tumor suppressors such as TP53, BAP1, and BECN1 downregulate SLC7A11 , increasing ferroptosis sensitivity ( 3.1.2 Relationship between lipid metabolism and ferroptosis PUFAs, particularly those containing bis-allylic hydrogen atoms such as arachidonate (AA) and adrenate (AdA), are highly susceptible to oxidation by ROS, making them central to ferroptosis ( Lipoxygenases (LOXs), iron-containing enzymes, play a direct role in inducing ferroptosis by catalyzing the peroxidation of membrane-bound PUFAs

[13] Individuals with limited dietary variety may benefit from supplementation even if consuming some animal products

Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis

Upon tissue disruption glucosinolates are enzymatically degraded by myrosinase and may yield a variety of biologically active products such as isothiocyanates, thiocyanates, nitriles and oxazolidine-2-thiones